Cutting Edge Clinical Research

BOLD: Burst DR Spinal Cord Stimulation Micro-dosing Stimulation in Patients with Back and Leg Pain.

Patient Population: Refractory Back and Leg Pain 

Device: Burst DR

Sponsor: Abbott

Enrollment: Closed

A Prospective, Non-Randomized, Open-Label, Multicenter Study Designed to Evaluate the Long-Term Safety of the Prometra II Programmable Pump System: Post Approval Study

Patient Population: Chronic Refractory Pain

Device: Prometra II Pump for Intrathecal Drug Delivery 

Sponsor: Flowonix

Enrollment: Closed

TARGET: A Post-Approval Study to Evaluate Targeted SCS (DRG) Stimulation for the management of Moderate to Severe Chronic, Intractable, Pain of the Lower Limbs due to CRPS types I and II

Patient Population: Lower Extremity Pain

Device: Abbott DRG Neurostimulator System

Sponsor: Abbott Medical

Enrollment: Closed

A Prospective, Multicenter, Randomized Double-Blind Study Examining the Safety and Efficacy of the Spinal Cord Stimulator (SCS) System with Feedback to treat patients with chronic pain of the trunk and/or limbs. 

Patient Population: Back and Leg Pain

Device: Evoke™ Spinal Cord Stimulator (SCS)

Sponsor: Saluda Medical

Enrollment: Closed

DELIVERY: A prospective randomized trial examining anatomic versus paraesthesia mapped placement of spinal cord stimulation (SCS) leads 

Patient Population: Back and Leg Pain

Device: Burst DR

Sponsor: Abbott

Enrollment: Closed

ReActiv8 Stimulation Therapy vs Optimal Medical Management: A Randomized Evaluation (RESTORE)

Patient Population: Axial back pain

Sponsor: Mainstay

Enrollment: Closed

SCOPE: A 5 year Superior IDS Clinical Outcomes Post Approval Evaluation

Patient Population: Back and Leg pain

Sponsor: Boston Scientific

Enrollment: Active

T2P: Spinal Cord Stimulation Trial to Permament Prediction Study

Patient Population: Back and leg pain

Sponsor: Abbott

Enrollment: Closed

Treatment of head pain with the SPRINT Peripheral Nerve Stimulation (PNS) System

Patient Population: Headache

Device: SPRINT PNS System

Sponsor SPR Therapeutics

Enrollment: Active

PROSPER: Post-Market,Randomized,Controlled,Prospective Study Evaluating Intrathecal Morphine (IT) versus Conventional Medical Management (CMM) in the Non-cancer, Refractory, Chronic Pain Population

Patient Population: Refractory Back and Leg Pain 

Device: Intrathecal Pump

Sponsor: Flowonix

Enrollment: Closed

PROLONG: Prospective, Multi-center, Open-label, Post-market Study

Patient Population: Refractory Back and Leg Pain with Failing Device

Device: Spinal Cord Stimulation

Sponsor: Abbott

Enrollment: Closed

PRESS 2: Postmarket Registry for Evaluation of the Superion Spacer

Patient Population: Spinal Stenosis

Device: Interspinous Spacer

Sponsor: Vertiflex

Enrollment: Closed

REALITY: Long-Term Real-World Outcomes Study on Patients Implanted With a Neurostimulator

Patient Population: Refractory Trunk and/or Limb Chronic Pain

Device: Spinal Cord Stimulation

Sponsor: Abbott

Enrollment: Closed

Noninvasive Thermal Nerve Block for Temporary Relief of Occipital Pain

Patient Population: Occipital Pain/Headache

Device: Thermaquil System

Sponsor: Thermaquil

Enrollment: Closed

SECURE: A Single arm, Multicenter, Prospective, Clinical Study on a Novel Minimally Invasive Posterior Sacroiliac Fusion Device

Patient Population: Sacroiliac joint dysfunction

Device: Linq System

Sponsor: PainTeq

Enrollment: Closed

ALIGN Study: A Retrospective, Multi-Center, Quantitative Analysis of Patients Baseline Pain Quality (PROMIS-29) Entering into Pain Practices in the United States

Patient Population: All New patients

Device: Celeri Health

Sponsor: Evolve

Enrollment: Closed

ASAP: A multicenter, Single-arm Registry Study examining the clinical workflow and multidimensional Assessment of chronic pain Patients presenting to chronic pain centers within the United States in the Real World

Patient Population: Neuromodulation Candidates

Device: Celeri Health

Sponsor: Evolve

Enrollment: Closed

THRIVE: Laboratory Analysis of Urinary Biomarkers and Correlation with Operationalized Validated Multidimensional Patient Reported Outcomes

Patient Population: All New patients

Device: Celeri Health and Ethos Laboratories

Sponsor: Evolve

Enrollment: Closed

ECAP Study: The study is evaluating the Evoke Closed-Loop SCS System, an investigational device designed to relieve chronic back and/or limb pain

Patient Population: Trunk and Limb Pain

Sponsor: Saluda Medical

Enrollment: Closed

REFINE Study: A Prospective, Observational, Open-Label, Non-Randomized,

Multi-Center Study Measuring Functional Outcomes in a Novel

Interspinous Fusion Device in Subjects with Low Back Pain

Patient Population: Back and Leg Pain

Sponsor: Aurora Spine

Enrollment: Active

SUPPORT Study: A Multicenter, Single-arm Registry Study examining laboratory urinary biomarkers, validated supplementation protocols and multidimensional  Assessment of chronic pain patients with active spinal cord  stimulation treatment in the United States

Patient Population: Patients with active SCS systems

Sponsor: Ethos

Enrollment: Closed